Andre Villas-Boas is likely to be without three key players as he takes his Tottenham side to the Emirates Stadium on Saturday.
Kyle Walker, Jermain Defoe and Aaron Lennon will be assessed on Wednesday after they all suffered hamstring injuries during their 2-1 defeat at Manchester City, which has prevented all them taking part in England's friendly with Sweden.
Walker was withdrawn mid way through the second hand at the Etihad and it was believed that his injury could have been worse than Lennon and Defoe's but as the pair have suffered from this type of injury before Spurs medical team have to ensure they do not risk the long term recurrences that can happen with these type of injuries.
Defoe’s absence would also be a significant blow, as he remains Spurs’ top scorer this season and, along with Adebayor, is one of only two senior strikers at the club.
Villas-Boas will be hoping for better news from Mousa Dembele. The Belgian midfielder has not played for Spurs since October after he was hit with the recurrence of a hip injury and is struggling to be fit for the trip to Emirates Stadium.
Spurs decided not to send Dembele for surgery to cure the problem but they have missed his energy and creativity in the centre and desperately need him to recover, with matches against Lazio, West Ham and Liverpool to follow the north London derby.
Younes Kaboul, Scott Parker and Benoit Assou-Ekotto also remain sidelined as Spurs approach an important period of their season.